Rabbit polyclonal antibody to Elk-1 (phospho Ser383)Elk-1 is a transcription factor that binds the serum response element (SRE) and mediates gene activity in response to serum and growth factors. Elk-1 is phosphorylated by MAP kinase pathways and appears to be a direct target of activated MAP kinase. Biochemical studies indicate that Elk-1 is a good substrate for MAP kinase. The kinetics of Elk-1 phosphorylation and activation correlate with MAP kinase activity. Other studies have shown that Elk-1 (Ser383) is also a target of the stress-activated kinase SAPK/JNK.
Modification
p-Ser383
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody detects 62 kDa phosphorylated Elk-1 (Ser383) of human, mouse and rat origins.:
This antibody is specific for Elk-1 (phospho Ser383).
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody detects 62 kDa phosphorylated Elk-1 (Ser383) of human, mouse and rat origins.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.