Rabbit polyclonal antibody to ELOA2SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A2 is transcriptionally active but its transcription activity is not enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).
Immunogen
The antiserum was produced against synthesized peptide derived from human ELOA2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAICC/IF
ELISA: 1:1000
Optimal dilutions should be determined experimentally by the end user.
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ElonginA2, RNA polymerase II transcription factor SIII subunit A2, TCEB3B, Transcription elongation factor B polypeptide3B, TCEB3L, ELOA2, Transcription elongation factor B polypeptide 3B, Elongin-A2, Elongin A2
Target
ELOA2
Molecular Weight(MW)
83 kDa (note)
Tissue Specificity
ELOA2 Antibody detects endogenous levels of total ELOA2 protein.
Application
Application
Immunofluorescence analysis of A549 cells, using ELOA2 Antibody. The picture on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:1000
Optimal dilutions should be determined experimentally by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.