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Elongin B antibody

Catalog Number:OM251325
OM251325
Discount Price
OM251325-100ul
1~2 Week
100ul
OM251325-50ul
50ul
OM251325-20ul
20ul
1~2 Week
Product Profile
Product Name Elongin B antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Elongin BThis gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]
Immunogen Recombinant protein of human TCEB2
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms TCEB2 , ELOB , SIII , transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Target Elongin B
Molecular Weight(MW) 13 KDa (note)
Application

Application

WB analysis of extracts from various cells using Elongin B antibody.

Application

ICC/IF analysis of U2OS cells using Elongin B antibody (red) and DAPI (blue).
Application Notes WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
Additional Information
Form Liquid
Storage Instructions Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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