Application
WB analysis of HepG2 cells using EMP2 antibody at 1.25μg/ml.Application
IHC-P analysis of human lung tissue using EMP2 antibody at 4.0-8.0μg/ml.| Product Name | EMP2 antibody, Internal |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to EMP2This gene encodes a tetraspan protein of the PMP22/EMP family. The encoded protein regulates cell membrane composition. It has been associated with various functions including endocytosis, cell signaling, cell proliferation, cell migration, cell adhesion, cell death, cholesterol homeostasis, urinary albumin excretion, and embryo implantation. It is known to negatively regulate caveolin-1, a scaffolding protein which is the main component of the caveolae plasma membrane invaginations found in most cell types. Through activation of PTK2 it positively regulates vascular endothelial growth factor A. It also modulates the function of specific integrin isomers in the plasma membrane. Up-regulation of this gene has been linked to cancer progression in multiple different tissues. Mutations in this gene have been associated with nephrotic syndrome type 10 (NPHS10). [provided by RefSeq, Mar 2015] |
| Immunogen | A synthetic peptide corresponding to an Internal region of Human EMP2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Cow: 82%; Human: 100% |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | EMP2 , XMP |
|---|---|
| Target | EMP2 |
| Molecular Weight(MW) | 19 KDa (note) |
Application
WB analysis of HepG2 cells using EMP2 antibody at 1.25μg/ml.
Application
IHC-P analysis of human lung tissue using EMP2 antibody at 4.0-8.0μg/ml.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
