Rabbit Polyclonal antibody to EphA2 (phospho Tyr588)This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EPHA2. The exact sequence is proprietary.
Modification
p-Tyr588
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CTPP1 CTRCT6 ARCC2 CTPA EPH receptor A2 ECK EPHA2
Target
EphA2 (phospho Tyr588)
Tissue Specificity
Recognizes endogenous levels of EPHA2 (pY588) protein.
Application
Application
Western blot analysis of EPHA2 (pY588) expression in A431 (A); H1299 (B) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.