| Gene Symbol |
EPHA2
|
| Gene Synonyms |
ECK CTPA ARCC2 CTPP1 CTRCT6 |
| Gene Full Name |
EPH receptor A2 |
| Gene Summary |
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.[provided by RefSeq, May 2010] |
| Alternative Names |
ARCC2 AW545284 CTPA CTPP1 CTRCT6 EC 2.7.10.1 Eck Eph receptor A2 EPHA2 EPHA2_HUMAN Ephrin receptor Ephrin receptor EphA2 Ephrin type A receptor 2 Ephrin type-A receptor 2 Epithelial cell kinase Epithelial cell receptor protein tyrosine kinase Myk 2 Myk2 Sek 2 Sek2 Soluble EPHA2 variant 1 Tyrosine protein kinase receptor ECK Tyrosine-protein kinase receptor ECK Tyrosine-protein kinase receptor MPK-5 Tyrosine-protein kinase receptor SEK-2 |
| Molecular Weight(MW) |
108 kDa |
| Cellular Localization |
Cell junction,Cell membrane,Cell projection,Membrane. |