Rabbit Polyclonal antibody to EphA7 (phospho Tyr608)This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Increased expression of this gene is associated with multiple forms of carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human EPHA7 (pY608). The exact sequence is proprietary.
Modification
p-Tyr608
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HEK11 EK11 EPHA7 EPH receptor A7 EHK-3 EHK3
Target
EphA7 (phospho Tyr608)
Tissue Specificity
Recognizes endogenous levels of EPHA7 (pY608) protein.
Application
Application
Western blot analysis of EPHA7 (pY608) expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.