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EPO receptor antibody

Catalog Number:OM251812
OM251812
Discount Price
OM251812-100ul
1~2 Week
100ul
OM251812-50ul
50ul
1~2 Week
Product Profile
Product Name EPO receptor antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [6G7] to EPO receptorThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Immunogen human rEPO receptor (extracellular domain)
Key Feature
Clonality Monoclonal
Isotype IgG2
Clone Number 6G7
Host Species Mouse
Tested Applications IHCWB
Western blotting(1:1000-2000)|Immunohistochemistry(1:50-300):
Species Reactivity Human
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms erythropoietin receptor
EPO-R
EPOR
Target EPO receptor
Tissue Specificity This antibody recognizes human EPO receptor in western blot. Reactivity to EPO receptor of other species is not tested.
Application

Application

Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining using (Proteinase K pretreatment is required).

Application

Buffered formalin fixed Human Tonsil tissue stained with (Antigen Retieval PK 20mgml in PBS)

Application

4% PFA fixed Human Placenta tissue stained with   (Antigen Retieval PK 20mgml in PBS)
Application Notes Western blotting(1:1000-2000)|Immunohistochemistry(1:50-300):
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer PBS
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