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Estrogen Receptor alpha antibody

Catalog Number:OM252074
OM252074
Discount Price
OM252074-100ul
1~2 Week
100ul
OM252074-50ul
50ul
1~2 Week
Product Profile
Product Name Estrogen Receptor alpha antibody
Antibody Type Primary Antibodies
Product description Mouse monoclonal antibody [10H12B10] to ESR1This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008]
Immunogen The immunogen corresponding to a region within amino acids 301 and 595 of ESR1 expressed in E. Coli.
Key Feature
Clonality Monoclonal
Isotype IgG1
Clone Number 10H12B10
Host Species Mouse
Tested Applications ELISAWB
ELISA: 1/10000.:
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms NR3A1
ESR1
ESRA
ERA
ER
ESR
Target ESR1
Application

Application

Western blot analysis using anti-ESR1 monoclonal antibody against truncated ESR1-His recombinant protein(1) and truncated Trx-ESR1 recombinant protein(2).
Application Notes ELISA: 1/10000.:
Additional Information
Form Liquid
Storage Instructions Store at 4℃, for long term storage, store at -20℃.
Storage Buffer Ascitic fluid containing 0.03% sodium azide.
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