Application
Western blot analysis using anti-ER-alpha monoclonal antibody against human breast carcinoma tissue lysate.Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using anti-ER-alpha antibody showing nuclear expression with DAB staining.| Product Name | Estrogen Receptor alpha antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [2B7] to ER-alphaThis gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to a region within amino acids 410 and 592 of human ER-alpha expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 2B7 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | ESR1 NR3A1 ESRA ESR ERA ER |
|---|---|
| Target | ER-alpha |
Application
Western blot analysis using anti-ER-alpha monoclonal antibody against human breast carcinoma tissue lysate.
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using anti-ER-alpha antibody showing nuclear expression with DAB staining.| Application Notes | ELISA: 1/10000.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Purified antibody in PBS containing 0.03% sodium azide. |
