Application
Western blot analysis of extracts from HepG2 tissue using Estrogen Receptor- beta (Phospho-Ser105) antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | Estrogen Receptor beta (phospho Ser105) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Estrogen Receptor beta (phospho Ser105)This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] |
| Immunogen | Peptide sequence around phosphorylation site of serine105(Q-R-S(p)-P-W) derived from Human Estrogen Receptor- beta. |
| Modification | p-Ser105 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | ESR-BETA NR3A2 ESR2 ESTRB Erb estrogen receptor 2 (ER beta) ER-BETA ESRB |
|---|---|
| Target | Estrogen Receptor beta (phospho Ser105) |
| Tissue Specificity | The antibody detects endogenous level of Estrogen Receptor- beta only when phosphorylated at serine 105. |
Application
Western blot analysis of extracts from HepG2 tissue using Estrogen Receptor- beta (Phospho-Ser105) antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20˚C/1 year |
| Storage Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
