| Product Name | Factor V Heavy chain antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [B10] to Factor V Heavy ChainThis gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq] |
| Immunogen | Purified human Factor V. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | B10 |
| Host Species | Mouse |
| Tested Applications | ELISAIHC-FIHC-P |
| This antibody can also be used for autoradiography.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | Factor V Heavy chain PCCF 2153 factor V FVL 227400 F5 P12259 |
|---|---|
| Target | Factor V Heavy chain |
| Tissue Specificity | This antibody reacts with the activation C peptide (mw ~150,000) in the heavy chain of thrombin-cleaved human Factor V. KD = 1.15 x 10 -10 mol/L. |
| Application Notes | This antibody can also be used for autoradiography.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS, pH7.2 |
