Rabbit Polyclonal antibody to FANCAThe Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human FANCA
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FA H FAH FA Fanconi anemia complementation group A FA1 FACA FAA FANCH
Target
FANCA
Application
Application
Western blot analysis of extracts of HeLa cells, using FANCA antibody.
Application
Immunohistochemistry of paraffin-embedded human stomach using FANCA antibody at dilution of 1:100 (x40 lens).