Application
Western blot analysis using anti-FBLN5 monoclonal antibody against truncated FBLN5-His recombinant protein.Application
Immunohistochemical analysis of paraffin-embedded human colon cancer(left) and breast cancer(right) showing cytoplasmic localization with DAB staining using anti-human FBLN5 antibody.| Product Name | FBLN5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1G6A4] to FBLN5The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq, Jul 2008] |
| Immunogen | The immunogen corresponding to a region within amino acids 242 and 448 of FBLN5 expressed in E. Coli. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | ELISAIHCIHC-PWB |
| ELISA: 1/10000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | FIBL-5 EVEC ARCL1A ADCL2 UP50 ARMD3 DANCE |
|---|
Application
Western blot analysis using anti-FBLN5 monoclonal antibody against truncated FBLN5-His recombinant protein.
Application
Immunohistochemical analysis of paraffin-embedded human colon cancer(left) and breast cancer(right) showing cytoplasmic localization with DAB staining using anti-human FBLN5 antibody.| Application Notes | ELISA: 1/10000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4℃, for long term storage, store at -20℃. |
| Storage Buffer | Ascitic fluid containing 0.03% sodium azide. |
