Application
Western blot analysis on (A) human stomach (B) fetal liver and (C) MCF-7 lysates using anti-FBP1 RabMAb (cat. #).| Product Name | FBP1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit monoclonal antibody [EPR4620] to FBP1FBP1 (Fructose-1,6-bisphosphatase 1) is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate . FBP1 catalyzes the removal of phosphate-1 from fructose 1,6-bisphosphate to produce fructose 6-phosphate, an important precursor in various biosynthetic pathways. It is a key, rate-controlling enzyme of gluconeogenesis, an important metabolic pathway that allows the cells to synthesize glucose and grow on non-carbohydrate carbon sources, such as glycerol, organic acids and amino acids . Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis . |
| Immunogen | A synthetic peptide corresponding to residues in human FBP1 was used as an immunogen. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIPWB |
| For WB: Use at a dilution of 1:1,000 - 10,000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | FBP1 FBP |
|---|---|
| Molecular Weight(MW) | 36 (note) |
Application
Western blot analysis on (A) human stomach (B) fetal liver and (C) MCF-7 lysates using anti-FBP1 RabMAb (cat. #).| Application Notes | For WB: Use at a dilution of 1:1,000 - 10,000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 °C. Stable for 12 months from date of receipt. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
