Rabbit Polyclonal antibody to FBXO6 (F-box protein 6)This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human FBXO6. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FBG2 antibody FBS2 antibody FBX6 antibody Fbx6b antibody FBXO6 antibody F-box/G-domain protein 2 antibody F-box protein Fbx6 antibody F-box protein FBG2 antibody F-box only protein 6 antibody F-box protein that recognizes sugar chains 2 antibody
Molecular Weight(MW)
34 kDa (note) (2)
Application
Application
Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE diluted at 1:500
Application
Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using FBXO6 antibody at 1:500 dilution.
Positive Control
293T
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.