Application
Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:500Application
Immunohistochemical analysis of paraffin-embedded human gastric cancer, using FBXO8 antibody at 1:500 dilution.Application
Sample (30 ug of whole cell lysate) A: JC 10% SDS PAGE diluted at 1:1000| Product Name | FBXO8 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FBXO8 (F-box only protein 8)This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human FBXO8. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FBS antibody FBX8 antibody FBXO8 antibody F-box/SEC7 protein FBS antibody F-box protein Fbx8 antibody F-box only protein 8 antibody F-box protein 8 antibody |
|---|---|
| Molecular Weight(MW) | 37 kDa (note) (2) |
Application
Sample (30 ug of whole cell lysate) A: Raji 10% SDS PAGE diluted at 1:500
Application
Immunohistochemical analysis of paraffin-embedded human gastric cancer, using FBXO8 antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: JC 10% SDS PAGE diluted at 1:1000| Positive Control | Raji , JC |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
