Application
WB analysis of extracts from various cell lines using Fe65 antibody.Application
ICC/IF analysis of U20S cells using Fe65 antibody (red) and DAPI (blue).Application
ICC/IF analysis of HeLa cells using Fe65 antibody.Application
IHC-P analysis of rat testis using Fe65 antibody at a dilution of 1:100.Application
IHC-P analysis of rat lung using Fe65 antibody at a dilution of 1:100.Application
IHC-P analysis of human lung cancer using Fe65 antibody at a dilution of 1:100.| Product Name | Fe65 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Fe65The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012] |
| Immunogen | Recombinant protein of human APBB1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | APBB1 , MGC:9072 , amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) , FE65 , RIR |
|---|---|
| Target | Fe65 |
| Molecular Weight(MW) | 77 kDa (note) |
Application
WB analysis of extracts from various cell lines using Fe65 antibody.
Application
ICC/IF analysis of U20S cells using Fe65 antibody (red) and DAPI (blue).
Application
ICC/IF analysis of HeLa cells using Fe65 antibody.
Application
IHC-P analysis of rat testis using Fe65 antibody at a dilution of 1:100.
Application
IHC-P analysis of rat lung using Fe65 antibody at a dilution of 1:100.
Application
IHC-P analysis of human lung cancer using Fe65 antibody at a dilution of 1:100.| Application Notes | WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
