Rabbit Polyclonal antibody to FesThis gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.[provided by RefSeq, Jan 2009]
Immunogen
Recombinant protein of human FES
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
feline sarcoma oncogene , FPS , FES
Target
Fes
Molecular Weight(MW)
93 kDa (note)
Application
Application
WB analysis of extracts from various cell lines using Fes antibody.
Application
IHC-P analysis of human stomach tissue using FES antibody at a dilution of 1:200.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.