Application
Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.Application
Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 ug/ml.Application
Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/ml.| Product Name | FGF4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to FGF4Fibroblast growth factor 4 (FGF4) is a member of the fibroblast growth factor (FGF) family that possess broad mitogenic and cell survival activities and play key roles in growth and survival of stem cells during embryogenesis, tissue regeneration, and carcinogenesis. FGF4 was identified by its strong oncogenic transforming activity and is a potent angiogenic factor, expressed in several highly vascularized tumors and also in adult mouse testis, intestine, and brain. Studies on the mouse homolog suggests a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. Furthermore, FGF4 regulates neural progenitor cell proliferation and neuronal differentiation. Recent studies show a growth-promoting role for FGF4 in human embryonic stem cells and a putative feedback inhibition mechanism by a novel FGF4 splice isoform that may serve to promote differentiation at a later stages of development. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Fibroblast growth factor 4, HBGF-4, FGF4, Heparin secretorytransforming protein, Fibroblast growth factor4, HST1, HST, Transforming protein KS3, HBGF4, Kaposi sarcoma oncogene, HST-1, Heparin secretory-transforming protein, HST 1, HBGF 4 |
|---|---|
| Target | FGF4 |
| Tissue Specificity | This antibody is specific for FGF4 |
Application
Immunofluorescence of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/mL.
Application
Western blot analysis of FGF4 in NIH 3T3 cell lysate with FGF4 antibody at (A) 0.5 and (B) 1 ug/ml.
Application
Immunocytochemistry of FGF4 in 3T3 cells with FGF4 antibody at 2.5 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85040-PEP - FGF4 Peptide Lysates: Cat. No. GTX27901 - 3T3 (NIH) Cell Lysate |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
