Rabbit Polyclonal antibody to Fgf8a (fibroblast growth factor 8 a)May convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through binding to the integrin cytoplasmic domain (By similarity). Induces cell migration and spreading mediated through integrin (possibly via focal adhesion complexes) (By similarity). Functions as a negative regulator of stress activated MAP kinase (MAPK) signaling pathways (By similarity). May play a role in regulation of apoptosis (By similarity). Interacts with and up-regulates PTK2 activity. Down regulates inositol 1,4,5-trisphosphate receptor-dependent calcium signaling.
Immunogen
Recombinant protein encompassing a sequence within the center region of zebrafish Fgf8a. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-W
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Zebra Fish
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)