Application
Sample (30 ug of whole cell lysate) A: HepG2 5% SDS PAGE diluted at 1:1000Application
FGFR2 antibody [C1C3] detects FGFR2 protein at cytosol on human brain by immunohistochemical analysis. Sample: Paraffin-embedded human brain. FGFR2 antibody [C1C3] dilution: 1:250.| Product Name | FGFR2 antibody [C1C3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FGFR2 (fibroblast growth factor receptor 2)The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human FGFR2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Xenopus laevis, Dog, Pig, Rabbit, Chicken, BovineMouse (99%), Rat (98%), Zebrafish (89%), Xenopus laevis (90%), Dog (99%), Pig (97%), Rabbit (84%), Chicken (97%), Bovine (98%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BEK antibody, BFR-1 antibody, CD332 antibody, CEK3 antibody, CFD1 antibody, ECT1 antibody, FLJ98662 antibody, JWS antibody, K-SAM antibody, KGFR antibody, TK14 antibody, TK25 antibody, FGFR2 antibody, fibroblast growth factor receptor 2 antibody, FGFR-2 an |
|---|---|
| Molecular Weight(MW) | 92 kDa (note) (9) |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein , Isoform 14: Secreted , Isoform 19: Secreted |
Application
Sample (30 ug of whole cell lysate) A: HepG2 5% SDS PAGE diluted at 1:1000
Application
FGFR2 antibody [C1C3] detects FGFR2 protein at cytosol on human brain by immunohistochemical analysis. Sample: Paraffin-embedded human brain. FGFR2 antibody [C1C3] dilution: 1:250.| Positive Control | HepG2 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
