Application
Immunofluorescence of FGFR3 in rat brain tissue with FGFR3 antibody at 20 ug/mL.Application
Western blot analysis of FGFR3 in SK-N-SH cell lysate with FGFR3 antibody at (A) 0.5 and (B) 1 ug/mL.Application
Immunohistochemistry of FGFR3 in rat brain tissue with FGFR3 antibody at 2.5 ug/mL.| Product Name | FGFR3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FGFR3This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Jul 2009] |
| Immunogen | FGFR3 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FGFR3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 1 - 2 ug/ml | |
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | JTK4 , fibroblast growth factor receptor 3 , CEK2 , CD333 , ACH , HSFGFR3EX |
|---|---|
| Target | FGFR3 |
| Tissue Specificity | FGFR3 antibody is human and rat reactive. At least three isoforms of FGFR3 are known to exist; this antibody will detect all three. |
Application
Immunofluorescence of FGFR3 in rat brain tissue with FGFR3 antibody at 20 ug/mL.
Application
Western blot analysis of FGFR3 in SK-N-SH cell lysate with FGFR3 antibody at (A) 0.5 and (B) 1 ug/mL.
Application
Immunohistochemistry of FGFR3 in rat brain tissue with FGFR3 antibody at 2.5 ug/mL.| Application Notes | WB: 1 - 2 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
