| Product Name | Fibrinopeptide A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [1F7] to Fibrinopeptide AFibrinogen is the main protein of the blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A and B are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerisation forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. |
| Immunogen | Human Fibrinopeptide A conjugated with a carrier protein. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | 1F7 |
| Host Species | Mouse |
| Tested Applications | ELISA |
| ELISA: As a capture antibody in a sandwich assay with an appropriate detection antibody. Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Synonyms | FGA Fibrinopeptide A Fibrinogen alpha/alpha E chain [Precursor] A alpha polypeptide Fib2 MGC119422 MGC119423 MGC119425 |
|---|---|
| Target | Fibrinopeptide A |
| Tissue Specificity | Fibrinopeptide A region in the alpha chain of fibrinogen and free fibrinopeptide A. |
| Cellular Localization | Secreted |
| Application Notes | ELISA: As a capture antibody in a sandwich assay with an appropriate detection antibody. Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | Phosphate-buffered saline, pH 7.4, containing 0.1% sodium azide |
