Application
Sample (30 ug of whole cell lysate) A: HCT116 12% SDS PAGE FMO5 antibody diluted at 1:1000Application
Immunohistochemical analysis of paraffin-embedded 4T1 xenograft, using FMO5 antibody at 1:500 dilution.| Product Name | FMO5 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FMO5 (flavin containing monooxygenase 5)Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human FMO5. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Rabbit, Bovine, Guinea pigMouse (87%), Rat (87%), Rabbit (89%), Bovine (93%), Guinea pig (89%) |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FMO5 antibody FMO 5 antibody dimethylaniline monooxygenase [N-oxide-forming] 5 antibody hepatic flavin-containing monooxygenase 5 antibody dimethylaniline oxidase 5 antibody flavin containing monooxygenase 5 antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa (note) (4) |
| Cellular Localization | Microsome membrane , Endoplasmic reticulum membrane |
Application
Sample (30 ug of whole cell lysate) A: HCT116 12% SDS PAGE FMO5 antibody diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded 4T1 xenograft, using FMO5 antibody at 1:500 dilution.| Positive Control | A549 , HeLa , HepG2 , HCT116 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
