Application
Immunofluorescence of FMR1 in human brain tissue with FMR1 antibody at 20 ug/mL.Application
Western blot analysis of FMR1 in rat brain tissue lysate with FMR1 antibody at 1 ug/ml.Application
Immunohistochemistry of FMR1 in human brain tissue with FMR1 antibody at 2.5 ug/mL.| Product Name | FMRP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FMRPThe protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010] |
| Immunogen | FMRP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human FMRP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
|
| Species Reactivity | HumanRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | POF1 fragile X mental retardation 1 POF FRAXA FMRP |
|---|---|
| Target | FMRP |
| Tissue Specificity | FMR1 antibody is human and rat reactive. Multiple isoforms of FMRP are known to exist. |
Application
Immunofluorescence of FMR1 in human brain tissue with FMR1 antibody at 20 ug/mL.
Application
Western blot analysis of FMR1 in rat brain tissue lysate with FMR1 antibody at 1 ug/ml.
Application
Immunohistochemistry of FMR1 in human brain tissue with FMR1 antibody at 2.5 ug/mL.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
