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OM683980
Discount Price
OM683980-100ul
100ul
Product Profile
Product Name Anti-Phospho-FMR1 (Ser500) antibody
Antibody Type Primary Antibodies
Immunogen Synthetic peptide conjugated with KLH.
Modification p-Ser500
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol FMR1
Gene Synonyms POF
FMRP
POF1
FRAXA
Gene Full Name fragile X messenger ribonucleoprotein 1
Gene Summary The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
Alternative Names FMR 1
Fmr1
Fmr1 gene
FMR1_HUMAN
FMRP
Fragile X mental retardation 1
Fragile X mental retardation 1 protein
Fragile X mental retardation protein 1
Fragile X mental retardation protein
fragile X mental retardation syndrome-related protein 1
fragile X mental retardation
autosomal homolog 1
FRAXA
fxr1
MGC87458
POF
POF1
Protein FMR-1
Protein FMR1
wu:fb16f11
wu:fd18c10
zgc:66226
Molecular Weight(MW) 71 kDa
Cellular Localization Cell membrane,Cell projection,Centromere,Chromosome,Cytoplasm,Membrane,Nucleus,Postsynaptic cell membrane,Synapse,Synaptosome.
Database Links
SwissProt ID Q06787
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% sodium azide,40% Glycerol.
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