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Anti-FMRP antibody

Catalog Number:OM662707
OM662707
Discount Price
OM662707-100ul
100ul
OM662707-50ul
50ul
OM662707-20ul
20ul
Product Profile
Product Name Anti-FMRP antibody
Antibody Type Primary Antibodies
Immunogen Polypeptide
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISA
ELISA:1:1000-10000
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Protein A
Target Information
Gene Symbol FMR1
Gene Synonyms Fmr-1
FMRP
FRAXA
POF
POF1
Gene Full Name fragile X messenger ribonucleoprotein 1
Gene Summary The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]
Alternative Names alternative splicing of exon 15
exons 15
16 and 17
FMRP
FMRP translational regulator 1
FMRP
contains neo-disrupted exon 5
alternatively spliced
MGC87458
protein FMR-1
RNA-binding protein
similar to fragile X mental retardation protein.
synaptic functional regulator FMR1
translational regulator
synaptic functional regulator
unnamed protein product
with exon 12
without exon 12
Molecular Weight(MW) 71kDa
Source Rabbit
Cellular Localization Cytoplasm, Cytoplasmic ribonucleoprotein granule;Cytoplasm, Stress granule;Cytoplasm;Perikaryon;Cytoplasm, perinuclear region;Cell projection, neuron projection;Cell projection, axon;Cell projection, dendrite;Cell projection, dendritic spine;Synapse, synaptosome;Cell projection, growth cone;Cell projection, filopodium tip;Synapse;Postsynaptic cell membrane;Presynaptic cell membrane;Nucleus;Nucleus, nucleolus;Chromosome, centromere;Chromosome;Cell membrane;Nucleus, Cajal body
Database Links
SwissProt ID Q06787
Application

ELISA

Coat the plate with immunizing antigen.Blue line: Immune serum; Orange line: Pre-immune serum.
Application Notes ELISA:1:1000-10000
Additional Information
Form Liquid
Storage Instructions Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C long term. Avoid freeze / thaw cycle.
Storage Buffer Purified antibody in PBS with 0.05% PC300,40% Glycerol.
validation
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