Mouse monoclonal antibody [JC12] to FOXP1This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Key Feature
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
JC12
Host Species
Mouse
Tested Applications
IHC-FIHC-PWB
Immunohistology - Paraffin: 1/200 - 1/500 Optimal dilution / concentration should be determined by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
forkhead box P1 hFKH1B QRF1 12CC4 HSPC215
Target
FOXP1
Tissue Specificity
This antibody recognizes human FOXP1 and does not recognize closely related molecules FOXP2, FOXP3 or FOXP4.
Application Notes
Immunohistology - Paraffin: 1/200 - 1/500 Optimal dilution / concentration should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.