Application
FPRL1 antibody detects FPRL1 protein by western blot analysis. HL-60 whole cell extracts and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FPRL1 antibody at a dilution of 1:1000 and developed with Trident femto Western HRP Substrate .| Product Name | FPRL1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to FPRL1 (formyl peptide receptor 2)Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4). |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human FPRL1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HM63 FMLPX LXA4R FPRH1 FMLP-R-II ALXR formyl peptide receptor 2 FPR2A FPRH2 FPR2 |
|---|---|
| Target | FPRL1 |
| Molecular Weight(MW) | 39 kDa (note) (2) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
Application
FPRL1 antibody detects FPRL1 protein by western blot analysis. HL-60 whole cell extracts and membrane extracts (30 μg) were separated by 10% SDS-PAGE, and the membrane was blotted with FPRL1 antibody at a dilution of 1:1000 and developed with Trident femto Western HRP Substrate .| Positive Control | HL-60 , HL-60 MF |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
