Rabbit Polyclonal antibody to FYB (FYN binding protein (FYB-120/130))Acts as an adapter protein of the FYN and LCP2 signaling cascades in T cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
Immunogen
Recombinant protein encompassing a sequence within the center region of human FYB. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (83%), Rat (83%), Bovine (86%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ADAP antibody PRO0823 antibody SLAP-130 antibody FYB antibody FYB-120/130 antibody adhesion and degranulation-promoting adaptor protein antibody p120/p130 antibody FYN-T-binding protein antibody SLP-76-associated phosphoprotein antibody FYN-bindin
Molecular Weight(MW)
85 kDa (note)
Application
Application
Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE diluted at 1:1000
Positive Control
293T , Jurkat , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.