Rabbit polyclonal antibody to Fyn (phospho Y530)This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq]
Modification
p-Tyr530
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHCIHC-P
Suggested starting dilutions are as follows. IHC: 1:50-1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MGC45350 SLK SYN
Target
Fyn (phospho Y530)
Cellular Localization
Present and active in lipid rafts. Present in cell body and along the process of mature and developing oligodendroyctes.
Application
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Fyn (Phospho-Tyr530) Antibody.
Application Notes
Suggested starting dilutions are as follows. IHC: 1:50-1:100. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.