Rabbit Polyclonal antibody to GAB1 (phospho Tyr627)The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Immunogen
A phospho specific peptide corresponding to residues surrounding Y627 of human GAB1
Modification
p-Tyr627
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFWB
WB: 1:500 - 1:200. IF: 1:100 - 1:200:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GRB2-associated binding protein 1 GAB1
Target
GAB1 (phospho Tyr627)
Molecular Weight(MW)
110 kDa (note)
Application
Application
ICC/IF analysis of methanol-fixed HeLa cells using GAB1 (phospho Tyr627) antibody.
Application
WB analysis of extracts from untreated and EGF-treated 293 cells using GAB1 (phospho Tyr627) antibody.
Application Notes
WB: 1:500 - 1:200. IF: 1:100 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.