Rabbit Polyclonal antibody to GAB1 (phospho Tyr627)The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GAB1 (pY627). The exact sequence is proprietary.
Modification
p-Tyr627
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GRB2-associated binding protein 1 GAB1
Target
GAB1 (phospho Tyr627)
Tissue Specificity
Recognizes endogenous levels of GAB1 (pY627) protein.
Application
Application
Western blot analysis of GAB1 (pY627) expression in Jurkat (A); K562 (B); NIH3T3 (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.