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GAB2 antibody

Catalog Number:OM253813
OM253813
Discount Price
OM253813-100ul
1~2 Week
100ul
OM253813-50ul
50ul
OM253813-20ul
20ul
1~2 Week
Product Profile
Product Name GAB2 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to GAB2 (GRB2-associated binding protein 2)This gene is a member of the GRB2-associated binding protein (GAB) gene family and is similar to the GAB1 gene. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq]
Immunogen Recombinant protein encompassing a sequence within the center region of human GAB2. The exact sequence is proprietary.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
*Optimal dilutions/concentrations should be determined by the researcher. :
Species Reactivity Human
Predicted Reactivity Mouse, RatMouse (91%), Rat (90%)
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms KIAA0571 antibody
GAB2 antibody
Grb2-associated binder 2 antibody
pp100 antibody
GRB2-associated-binding protein 2 antibody
growth factor receptor bound protein 2-associated protein 2 antibody
GRB2-associated binding protein 2 antibody
Molecular Weight(MW) 74 kDa (note) (3)
Application

Application

Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE diluted at 1:1000
Positive Control NT2D1 , IMR32 , U87-MG , MCF-7
Application Notes *Optimal dilutions/concentrations should be determined by the researcher. :
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
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