Application
Western Blot: GABA A Receptor beta 1 Antibody [ - Rat cerebellar (Cb) and hippocampal (Hipp) lysates showing specific immunolabeling of the ~55k ß1-subunit of the GABAA-R.| Product Name | GABA A Receptor beta 1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GABA A receptor beta 1GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics. |
| Immunogen | Fusion protein of MBP with the amino acid sequence representing the cytosolic loop of the rat GABA-A receptor beta 1 subunit. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| We recommend the following starting dilutions: Western Blot 1:1,000. Optimal concentration should be determined experimentally by the end user.: |
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| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Gene Synonyms | 25450 GABA A receptor beta1 GABRB1 2560 14400 |
|---|---|
| Target | GABA A receptor beta 1 |
| Tissue Specificity | NB300- 197 reacts with the 51-54 kDa beta 1 subunit of rat brain GABA-A. There is no known reactivity with other GABA subunits. There is no homology with other GABA subunits. |
| Cellular Localization | Integral membrane protein |
Application
Western Blot: GABA A Receptor beta 1 Antibody [ - Rat cerebellar (Cb) and hippocampal (Hipp) lysates showing specific immunolabeling of the ~55k ß1-subunit of the GABAA-R.| Application Notes | We recommend the following starting dilutions: Western Blot 1:1,000. Optimal concentration should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
