Rabbit Polyclonal antibody to GABRG2This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Immunogen
KLH conjugated synthetic peptide derived from human GABRG2/GABA A Receptor gamma 2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB(1:100-500), IHC-P(1:100-500):
Species Reactivity
MouseRat
Predicted Reactivity
Bovine, Horse, Pig, Dog
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
gamma-aminobutyric acid (GABA) A receptor gamma 2 ECA2 GEFSP3 CAE2
Target
GABRG2
Tissue Specificity
GABRG2/GABA A Receptor gamma 2
Application
Application
IHC-P analysis of rat brain using GABRG2 antibody at a dilution of 1:200.
Application
WB analysis of human colon carcinoma (lane 1) and mouse brain (lane 2) lysates using GABRG2 antibody at a dilution of 1:200.
Application Notes
WB(1:100-500), IHC-P(1:100-500):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.