Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytosol on human brain by immunohistochemical analysis. Sample: Paraffin-embedded human brain. GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:250.Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABBR1 protein by Western blot analysis. A. 30 µg PC-3 whole cell lysate/extract B. 30 µg U87-MG whole cell lysate/extract C. 30 µg SK-N-SH whole cell lysate/extract 7.5 % SDS-PAGE GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:500Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm by immunofluorescent analysis. Sample: SH-SY5Y cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GABA B Receptor 1 protein stained by GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500. Red: SOX2 protein stained by SOX2 antibody diluted at 1:200. Blue: Hoechst 33342 staining.Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm by immunofluorescent analysis. Sample: U-87 MG cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GABA B Receptor 1 protein stained by GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500. Blue: Hoechst 33342 staining.Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABBR1 protein by Western blot analysis. A. 30 µg C8D30 whole cell lysate/extract 7.5 % SDS-PAGE GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:500Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500.| Product Name | GABA B Receptor 1 antibody , Internal |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to GABA B Receptor 1 (gamma-aminobutyric acid (GABA) B receptor, 1)Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human GABA B Receptor 1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | Pig, Rhesus Monkey, BovinePig (100%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FLJ92613 antibody GABABR1 antibody GABBR1-3 antibody GB1 antibody GPRC3A antibody dJ271M21.1.1 antibody dJ271M21.1.2 antibody GABBR1 antibody GABA-BR1 antibody seven transmembrane helix receptor antibody GABAB subunit 1c antibody gamma-aminobut |
|---|---|
| Molecular Weight(MW) | 108 kDa (note) (4) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane; Multi-pass membrane protein , Isoform 1E: Secreted |
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytosol on human brain by immunohistochemical analysis. Sample: Paraffin-embedded human brain. GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:250.
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABBR1 protein by Western blot analysis. A. 30 µg PC-3 whole cell lysate/extract B. 30 µg U87-MG whole cell lysate/extract C. 30 µg SK-N-SH whole cell lysate/extract 7.5 % SDS-PAGE GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:500
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm by immunofluorescent analysis. Sample: SH-SY5Y cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GABA B Receptor 1 protein stained by GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500. Red: SOX2 protein stained by SOX2 antibody diluted at 1:200. Blue: Hoechst 33342 staining.
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm by immunofluorescent analysis. Sample: U-87 MG cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: GABA B Receptor 1 protein stained by GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500. Blue: Hoechst 33342 staining.
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABBR1 protein by Western blot analysis. A. 30 µg C8D30 whole cell lysate/extract 7.5 % SDS-PAGE GABA B Receptor 1 antibody [N2C1], Internal dilution: 1:500
Application
GABA B Receptor 1 antibody [N2C1], Internal detects GABA B Receptor 1 protein at cytoplasm in rat brain by immunohistochemical analysis. Sample: Paraffin-embedded rat brain. GABA B Receptor 1 antibody [N2C1], Internal diluted at 1:500.| Positive Control | PC-3 , U87-MG , SK-N-SH , C8D30 |
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| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
