Rabbit Polyclonal antibody to GADD45AThis gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]
Immunogen
Recombinant protein of human GADD45A
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHC-PWB
WB: 1:500 - 1:200. IHC: 1:50 - 1:200:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
growth arrest and DNA-damage-inducible alpha GADD45 DDIT1
Target
GADD45A
Molecular Weight(MW)
18 kDa (note)
Application
Application
ICC/IF analysis of A549 cells using GADD45A antibody.
Application
WB analysis of extracts from various tissued using GADD45A antibody.
Application
IHC-P analysis of human esophagus tissue using GADD45A antibody at a dilution of 1:100.
Application Notes
WB: 1:500 - 1:200. IHC: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.