Immunohistochemistry analysis of paraffin-embedded human brain, using GADD45GIP1 Antibody. The picture on the right is treated with the synthesized peptide.
Rabbit polyclonal antibody to GADD45GIP1Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity.
Immunogen
The antiserum was produced against synthesized peptide derived from human GADD45GIP1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCIHC-P
ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Papillomavirus L2-interacting nuclear protein 1 Growth arrest and DNAdamageinducible proteinsinteracting protein 1 p53responsive gene 6 protein GADD45GIP1 Papillomavirus L2interacti
Target
GADD45GIP1
Molecular Weight(MW)
25 kDa (note)
Tissue Specificity
GADD45GIP1 Antibody detects endogenous levels of total GADD45GIP1 protein.
Application
Application
Immunohistochemistry analysis of paraffin-embedded human brain, using GADD45GIP1 Antibody. The picture on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:40000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 203% glycerol.