Application
Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody diluted by 1:1000.Application
Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody diluted by 1:1000.| Product Name | gamma Sarcoglycan antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to gamma Sarcoglycan (sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein))This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C). [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human gamma Sarcoglycan. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | MouseRat |
| Predicted Reactivity | Human, Dog, Rabbit, BovineHuman (100%), Dog (94%), Rabbit (88%), Bovine (83%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | SGCG , DAGA4 , sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) , SCG3 , TYPE , DMDA1 , A4 , DMDA , SCARMD2 , LGMD2C , MAM |
|---|---|
| Target | gamma Sarcoglycan |
| Molecular Weight(MW) | 32 kDa (note) (2) |
| Cellular Localization | Cell membrane , sarcolemma; Single-pass type II membrane protein (By similarity) , Cytoplasm , cytoskeleton |
Application
Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Rat tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody diluted by 1:1000.
Application
Gamma Sarcoglycan antibody detects Gamma Sarcoglycan protein by western blot analysis. Mouse tissue extracts (50 μg) was separated by 12 % SDS-PAGE, and the membrane was blotted with Gamma Sarcoglycan antibody diluted by 1:1000.| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
