Application
Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE GCS-alpha-3 antibody diluted at 1:1000| Product Name | GCS-alpha-3 antibody [C1C3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GCS-alpha-3 (guanylate cyclase 1, soluble, alpha 3)Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit, such as alpha-1 (GUCY1A3), and a beta subunit, typically beta-1 (GUCY1B3; MIM 139397), catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).[supplied by OMIM] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human GCS-alpha-3. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Japanese medaka, Dog, Pig, BovineMouse (97%), Rat (97%), Zebrafish (83%), Japanese medaka (80%), Dog (98%), Pig (97%), Bovine (96%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | GC-SA3 antibody, GUC1A3 antibody, GUCA3 antibody, GUCSA3 antibody, GUCY1A1 antibody, GUCY1A3 antibody, guanylate cyclase soluble subunit alpha-3 antibody, GC-S-alpha-1 antibody, soluble guanylate cyclase large subunit antibody, GCS-alpha-1 antibody, GCS-al |
|---|---|
| Target | GCS-alpha-3 |
| Molecular Weight(MW) | 77 kDa (note) (7) |
| Cellular Localization | Cytoplasm |
Application
Sample (30 ug of whole cell lysate) A: 293T 7.5% SDS PAGE GCS-alpha-3 antibody diluted at 1:1000| Positive Control | 293T |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
