| Product Name | GCSF Receptor antibody [S-1284] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [S-1284] to CSF3RThe protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia. [provided by RefSeq, Aug 2010] |
| Immunogen | Purified recombinant maltose-binding protein / granulocyte colony stimulating factor receptor (MBP-G-CSF-R) fusion protein |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | S-1284 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-PWB |
| This antibody, at a concentration of 1-10 μg/ml, will allow visualization of 0.25 μg/lane of human G-CSFR-MBP. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Gene Synonyms | GCSFR , CD114 |
|---|---|
| Target | CSF3R |
| Tissue Specificity | G-CSF-R. This antibody does not cross-react with MBP or BSA (bovine serum albumin). |
| Cellular Localization | Type I membrane protein. Isoform GCSFR2, which lacks the transmembrane domain, may represent a soluble form of the receptor. |
| Light Chain Type | kappa |
| Application Notes | This antibody, at a concentration of 1-10 μg/ml, will allow visualization of 0.25 μg/lane of human G-CSFR-MBP. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 0.01M PBS, pH 7.2 |
