Rabbit Polyclonal antibody to GDF8The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human MSTN
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCIHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:100
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MSTN , MSLHP , myostatin
Target
GDF8
Molecular Weight(MW)
43 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using MSTN antibody.
Application
Immunohistochemistry of paraffin-embedded mouse lung using MSTN antibody at dilution of 1:100 (40x lens).