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GDNF Receptor alpha 1 antibody

Catalog Number:OM254372
OM254372
Discount Price
OM254372-100ul
1~2 Week
100ul
OM254372-50ul
50ul
OM254372-20ul
20ul
1~2 Week
Product Profile
Product Name GDNF Receptor alpha 1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to GDNF Receptor alpha 1Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Feb 2009]
Immunogen GFR alpha 1 antibody was raised against a 14 amino acid peptide near the center of human GFR alpha 1.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAIHC-PWB
WB: 1 ug/ml. IHC-P: 1 ug/ml
Species Reactivity Human
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms TRNR1 , RET1L , GDNFRA , GFRA1 , GDNFR , GFR-ALPHA-1 , GDNF family receptor alpha 1 , RETL1
Target GDNF Receptor alpha 1
Tissue Specificity GFR alpha 1 antibody is predicted to not cross-react with other members of the GFR alpha family of proteins.
Application

Application

Immunohistochemistry of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 1 ug/mL.

Application

Western blot analysis of GFR alpha 1 in crude membrane fractions of human brain (B), liver (L), kidney (K), and spleen (S), respectively, with GFR alpha 1 antibody at 1 ug/mL.
Application Notes WB: 1 ug/ml. IHC-P: 1 ug/ml
Additional Information
Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer PBS containing 0.02% sodium azide.
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