Rabbit polyclonal antibody to GFR alpha 4Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Immunogen
The antiserum was produced against synthesized peptide derived from human GFR alpha 4.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GFR-alpha-4 GDNF family receptor alpha4 GFRA4 Persephin receptor GFRalpha4 GDNF family receptor alpha-4 GFR alpha 4 GDNF family receptor alpha 4
Target
GFR alpha 4
Molecular Weight(MW)
31 kDa (note)
Tissue Specificity
GFR alpha 4 Antibody detects endogenous levels of total GFR alpha 4 protein.
Application
Application
Western blot analysis of extracts from HeLa cells, using GFRA4 Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.