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GIPR antibody, N-term

Catalog Number:OM254581
OM254581
Discount Price
OM254581-100ul
1~2 Week
100ul
OM254581-50ul
50ul
OM254581-20ul
20ul
1~2 Week
Product Profile
Product Name GIPR antibody, N-term
Antibody Type Primary Antibodies
Product description Rabbit polyclonal to GIPR (N-term)Gastric inhibitory polypeptide (GIP; MIM 13724), also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. It was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. It is involved in several other facets of the anabolic response.[supplied by OMIM]
Immunogen KLH conjugated synthetic peptide between 15~45 amino acids from the N-terminal region of human GIPR.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications FACSIHC-PWB
ELISA: Use at 1:1,000:
Species Reactivity Human
Concentration 0.2mg/ml
Target Information
Gene Synonyms GIP-R
Gastric inhibitory polypeptide receptor
GIPR
Glucose-dependent insulinotropic polypeptide receptor
Glucosedependent insulinotropic polypeptide receptor
GIP R
Target GIPR
Molecular Weight(MW) 53.157 kDa (note)
Application

Application

GIPR Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Application

GIPR Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GIPR Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

Western blot analysis of GIPR antibody (N-term) in HL60 cell line lysates (35ug/lane). GIPR (arrow) was detected using the purified Pab.
Application Notes ELISA: Use at 1:1,000:
Additional Information
Form Liquid
Storage Instructions Store at at 2-8°C for up to 6 months. For long term storage, aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Storage Buffer PBS with 0.09% (W/V) sodium azide
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