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GLE1 antibody

Catalog Number:OM254627
OM254627
Discount Price
OM254627-100ul
1~2 Week
100ul
OM254627-50ul
50ul
OM254627-20ul
20ul
1~2 Week
Product Profile
Product Name GLE1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to GLE1This gene encodes a predicted 75-kDa polypeptide with high sequence and structure homology to yeast Gle1p, which is nuclear protein with a leucine-rich nuclear export sequence essential for poly(A)+RNA export. Inhibition of human GLE1L by microinjection of antibodies against GLE1L in HeLa cells resulted in inhibition of poly(A)+RNA export. Immunoflourescence studies show that GLE1L is localized at the nuclear pore complexes. This localization suggests that GLE1L may act at a terminal step in the export of mature RNA messages to the cytoplasm. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen Gle1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human Gle1.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ELISAICC/IFIHC-PWB
IF: 5 ug/mL:
Species Reactivity Mouse
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms GLE1L
LCCS1
GLE1 RNA export mediator
LCCS
hGLE1
Target GLE1
Application

Application

Immunofluorescence of gle1 in mouse brain tissue with gle1 antibody at 5 ug/mL.

Application

Western blot analysis of Gle1 in mouse brain tissue lysate with Gle1 antibody at (A) 1 and (B) 2 ug/mL.

Application

Immunohistochemistry of Gle1 in mouse brain tissue with Gle1 antibody at 2.5 ug/mL.
Application Notes IF: 5 ug/mL:
Additional Information
Form Liquid
Storage Instructions Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer PBS containing 0.02% sodium azide.
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