Rabbit Polyclonal antibody to GLRBThis gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Immunogen
KLH conjugated synthetic peptide derived from human GLRB (23-110aa)
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P(1:100-500):
Species Reactivity
Rat
Predicted Reactivity
Bovine, Rabbit, Horse, Sheep, Pig, Chicken, Dog
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
HKPX2 glycine receptor beta
Target
GLRB
Tissue Specificity
GLRB
Application
Application
IHC-P ImageIHC-P analysis of rat brain using GLRB antibody at a dilution of 1:200.
Application Notes
IHC-P(1:100-500):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.