Application
ApplicationApplication
Western Blot: Glutamate receptor 2 [Phospho-Ser880] Antibody [ - rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).| Product Name | GluR2 (phospho Ser880) antibody |
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| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to GluR2 (phospho Ser880)Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser880 conjugated to KLH. |
| Modification | p-Ser880 |
| Clonality | Polyclonal |
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| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Optimal working dilutions should be determined experimentally by the end user.: |
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| Species Reactivity | Rat |
| Predicted Reactivity | chicken, human, mouse, non-human primate and Zebrafish(100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HBGR2 GluR-K2 GluRK2 GRIA2 GLURB GluA2 GLUR2 GluR K2 GluR2-subunit (phospho S880) GluR2-subunit (phospho Ser880) GluR2-subunit (pS880) GluR2-subunit (pSer880) GluR2-subunit phospho S880 GluR2-subunit phospho Ser880 Phospho GluR2-subunit (S880 |
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| Target | GluR2 (phospho Ser880) |
| Molecular Weight(MW) | 100 (note) |
| Cellular Localization | Interaction with CACNG2 promotes cell surface expression. |
Application
Application
Application
Western Blot: Glutamate receptor 2 [Phospho-Ser880] Antibody [ - rat brain homogenate showing specific immunolabeling of the ~100k GluR2 protein phosphorylated at Ser880 (control). Immunolabeling is blocked by preadsorption with the phospho-peptide used as antigen (Peptide) but not by the corresponding dephospho-peptide (not shown).| Application Notes | Optimal working dilutions should be determined experimentally by the end user.: |
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| Form | Liquid |
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| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
